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Effects of tirzepatide, a dual GIP and GLP-1 receptor agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats

Mazdutides GLORY-2 Phase 3 trial, conducted in Chinese adults with obesity, found that participants on the 9 mg dose lost an average of 16.65% of body weight over 60 weeks, compared with 1.5% in the placebo group

Ongoing Studies (Non-Analytical) Three additional ongoing studies (two interventional and one observational) were identified that compare tirzepatide with semaglutide or bariatric surgery

Signs your maintenance dose may need adjusting Sometimes your body sends signals that your maintenance dose needs fine-tuning

By stimulating these receptors, tirzepatide enhances insulin secretion when blood sugar levels rise, helping to lower glucose levels after meals