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comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site

These medications work by mimicking natural incretin hormones, which slow gastric emptying, enhance insulin secretion, suppress glucagon release, and reduce appetite through central nervous system pathways

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By improving insulin production, minimizing glucagon secretion, and impacting areas in the brain that control appetite, semaglutide can help reduce hunger and promote feelings of fullness