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For example, pancreatitis and gallbladder-related problems are closely monitored in all incretin-based drug trials, but so far, retatrutide has not been associated with a statistically significant increase in these conditions compared with placebo arms

The absolute contraindications (thyroid cancer history, MEN2) are rare conditions

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Exendin 939 did not affect proton-induced TRPV1 activation, suggesting its selective antagonism