glp-1 and hs drugs linked to reduced symptoms in chronic skin condition hidradenitis suppurativa Glucagon-like peptide-1 receptor: mechanisms and

I nailed it.

However, the catabolic qualities of glucagon, notably its effect to decrease hepatic fat and circulating lipids, could be leveraged for therapeutic benefit in metabolic diseases if its diabetogenic action were mitigated

GLP-1 receptor agonists have well-characterized safety profiles based on extensive use in diabetes and obesity management, but specific considerations apply when considering their use in patients with substance use disorders

Studies in pancreatic cells had demonstrated that GLP-1(2836) stimulates cAMP/PKA (27), a key upstream signaling pathway in pharmacological and ischemic preconditioning (28)