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Conclusion The endothelial glycocalyx plays a central role in maintaining vascular health via its regulation of vascular permeability and its mechanical ability to transduce shear stress and facilitate production of NO

As a compounded MOTS-C peptide, proper handling is critical to maintain its integrity

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S., Du, J., Sthiannopkao, S., Xing, G

Using RNA interference strategies Blanger and collaborators observed that a similar decrease in Glo-1 activity (80%) does not impact astrocytic and neuronal cell viability to the same extent using primary mouse cortical cultures as a model (Blanger et al., 2006b)