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Although, the composition and position (i.e., intra- or extracellular) of protein aggregates are different from disease to disease, this common characteristic shows that protein deposition per se , or some related event, is toxic to neurons (Dauer and Przedborski, The pathological changes of PD are characterized by degeneration of DA neurons in the substantia nigra and formation of Lewy body (LB) in neurons (Scherfler et al., 2007)

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First isolated from human gastric juice in 1993 by Croatian researchers, this 15-amino acid peptide demonstrates remarkable tissue-protective properties across multiple organ systems

Nonalcoholic fatty liver disease: An emerging driver of cardiac arrhythmia