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In VRK2-high tumors, VRK2 promotes SLC7A11 trafficking from the ER to the Golgi, enhancing GSH synthesis and conferring resistance to GSH inhibition
Moreover, scholarly investigations and empirical findings posit that immunotherapy exhibits a comparatively lower efficacy in addressing solid tumors in contrast to lymphoma (119)

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Reduced abdominal fat, improved metabolic function, and better insulin sensitivity
