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In that context, it is noteworthy that optimal function of stem cells depends on their highly specialized microenvironment, or niche [30, 31], and SASP factors deleteriously affect stem cells by altering this niche [32, 33]

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That is important, because it confirms that VEGFR2 is not just one of many mechanisms, but truly a causal pathway

My husband had heart palpitations earlier on
