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Description
It is found in every cell of the body and serves as the first line of defense, with particularly high le

It then inhibits adipocyte lipolysis and increases FFAs in cells, further stimulating the LDLs accumulation and secretion, inducing lipid metabolism disorders, lipotoxicity, and even cell necrosis, finally resulting in diabetic myocardial damage

Sung HK, Chan YK, Han M, Jahng JWS, Song E, Danielson E et al (2017) Lipocalin-2 (NGAL) attenuates autophagy to exacerbate cardiac apoptosis induced by myocardial ischemia

With respect to the frequency of the severe deficiency, the variation between the different populations is notorious

Regular B12 supplementation is necessary to maintain optimal levels and prevent deficiency from occurring again
