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A growing body of evidence suggests that phenotypic changes in macrophages play a critical role in the development and progression of CKD (Chung et al., 2023)

The data generated during this phase help define the dose range that may be explored in subsequent studies and contribute to understanding exposure-response relationships, pharmacokinetic behavior and safety considerations associated with the investigational compound

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The GLUT family of transporters can be divided into three classes based upon primary amino acid sequence comparisons

- Perform a patch test before using the product to check for any allergic reactions