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Description
T-helper type 1 cytokine release is enhanced by in vitro zinc supplementation due to increased natural killer cells
Potential reasons for reduced activity include genetic variants, nutrient insufficiencies in key cofactors, chronic inflammatory load, and interference from toxic metals or chemicals
CoQ10 , a mitochondrial antioxidant, was tested at high doses in early Parkinsons and in Huntingtons and showed no benefit, though it retains a role in blood pressure and in primary CoQ10 deficiency

Real life matters
One study showed that an intervention consisting of 500 mg vitamin C twice daily for 2 months improved iron status and corrected anemia in a population of vegetarians (Sharma 1995)