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The different mutations in SLC22A5 probably give rise to differences in severity/onset of the disease

Fish odour syndrome with features of both primary and secondary trimethylaminuria

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However, we found low heterogeneity between the five trials in all-cause mortality (I 2 = 22%) (Figure 2) and detected no heterogeneity between the two trials reporting heart failure (I 2 = 0%), unstable angina (I 2 = 0%), and myocardial reinfarction (I 2 = 0%) (Figure 3)
