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Collectively, targeting ferroptosis by inhibiting GPX4 in intratumoral Tregs seems to be a promising strategy for reprogramming the TME and treating cancer

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Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis

To date, hundreds of metabolomics studies have been conducted to investigate the metabolite alterations in animal models of depression, which expanded the knowledge of the physiopathology of depression [10,11,12]