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Description
Temporal associationwhere acne develops shortly after starting B12 and improves after stoppingprovides the strongest clinical evidence for causation in individual cases
doi:10.2165/00003088-198409060-00002 167
Legal status (US): MK-677 is not FDA-approved for any human indication
Most patients receive it once daily, often in the morning to coincide with the bodys natural metabolic cycle
Constipation: Less common than diarrhea but still possible
