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In comparison to patients on diet and placebo only, the patients treated with orlistat demonstrated a significant improvement in blood glucose concentrations, insulin resistance, waist circumference, total and low-density lipoprotein cholesterol (LDL-C), and blood pressure [35-37]

Guyenet SJ, Furrer SA, Damian VM, Baughan TD, La Spada AR, Garden GA

doi: 10.1016/j.ygeno.2005.01.006
