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It seems that low B12 status is associated with lower muscle mass and maybe muscle strength. Subtle deficiency may carry broad risk B12 deficiency remains widespread across the globe, particularly among older adults and in populations with limited access to animal-based foods, which are primary sources of the vitamin

Many seaweeds have B12 analogues through their symbiotic relationship with cobalamin-producing bacteria

Macrocyclic peptides as allosteric inhibitors of nicotinamide N -methyltransferase (NNMT)