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Similarly, citronellol promotes necroptosis through TNF- and biphasic production of ROS, inhibiting tumor growth in xenograft models (YU et al

doi: 10.1016/j.jhep.2020.12.031 100 LiYYangJZhangQXuSSunWGeSet al

6.5 Structural biology and payload-target interactions The successful integration of novel payloads into ID-ADCs fundamentally relies on structural biology, which enables rational design by elucidating specific interactions between the payload and its target

Hum Mol Genet (2010) 19(23):464353

These are not randomized controlled trials
