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Accessed August 8, 2025

A.Del ValleP.GuptaS.BensonD

Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis

The basic metabolic parameters (metabolic activity, cell cycle analysis, LDH release, caspase-3 activity) and the protein expression of sequestosome 1 (SQSTM/p62), proliferating cell nuclear antigen (PCNA), proto-oncogene tyrosine-kinase (c-SRC), superoxide dismutase-1 (SOD1), AhR, Beclin1, and extracellular signal-regulated kinas-1/2 (ERK1/2) were measured

Further studies are needed to elucidate the specific molecular mechanisms of oxidative stress in TAO and to assess the safety and efficacy of therapeutic agents targeting these pathways