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doi: 10.3389/fcimb.2018.00316 83 HijaziS.ViscaP.FrangipaniE

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The amounts of total reduced and oxidized glutathione were quantified using a modified Tietze method by Adams ( Safety Measurements Any adverse event during the course of the study was monitored and reported to the study staff at week 6 (visit 5) or week 12 (visit 8) in the clinic or directly to the principal investigator throughout the study

References Balooch Hasankhani M, Mirzaei H, Karamoozian A

In fact, since B12 deficiencies can lead to mood changes, proper supplementation often helps improve mood-related issues