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however, deletion of both MSR and CD36 greatly reduces lesion complexity and vulnerable plaques, the most critical aspect of lesion development (347)
The system that removes these toxic reactive oxygen species includes a host of enzymes including four enzymes Glutathione peroxidase (GPX)- GPX detoxifies peroxides with glutathione acting as an electron donor in the reduction reaction, producing glutathione disulfide as an end product
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