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in this form it is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine (a reaction which also requires folate)

Others who may be more susceptible to vitamin B12 deficiency are patients diagnosed with Crohns disease or celiac disease, and those who have undergone intestinal procedures such as weight loss surgery

B12 injections effectively treat deficiency symptoms including chronic fatigue, mental fog, memory problems, numbness or tingling in extremities, pale skin, general weakness, and irritability in affected patients.

Reducing the likelihood of severe illnesses

The shelf life of a supplement depends on its form, its contents, and how someone is storing it