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Description
Ipamorelin is a 5-amino-acid pentapeptide that binds the ghrelin receptor (GHSR1a) on the same pituitary cells
Apart from its beneficial functions on stem cell regeneration and neurogenesis, accumulating evidence shows that LIF plays essential roles during oligodendrocyte maturation and function in the context of autoimmune inflammation and remyelination (102107)
This is clinically relevant, as IGF-I is generally less reliable of a biomarker for screening adults above 60 years with GHD and is a better screening and diagnostic biomarker in GHD in subjects with disease onset in childhood or early adulthood (86)
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