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Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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This is a large-scale randomised controlled trial which aims to investigate the effect of maternal vitamin B 12 supplement during pregnancy through 6 months postpartum on early child development and growth