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The two main metabolic functions of carnitine are to facilitate fatty acyl group transport into mitochondria and to maintain the ratio of acyl-CoA to free CoA in the mitochondria:[14] 1) Carnitine is an essential amino acid necessary for the beta-oxidation of fatty acids and energy production in mitochondria

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 35% by weight of the carbomer

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