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When the PRP is injected into a site of injury, the tissue is prompted to release growth factors and draw in additional cells to aid in the healing process

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Macrophages are crucial effector cells in the pathological process of RA, which can interact with T, B, and fibroblast-like synovial cells to produce large amounts of cytokines, chemokines, digestive enzymes, prostaglandins, and reactive oxygen species to accelerate bone destruction
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