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Similarly, ongoing research into ME/CFS has demonstrated the direct, measurable clinical benefits of targeted antioxidant therapy on the central nervous system

80 It has been reported that impaired thioredoxin expression in spontaneously hypertensive rats 81 and in endothelial cells negatively regulates ROS production in VSMC through thioredoxin upregulation

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

The pathophysiologic mechanism of hyperpigmentation involves increased melanin synthesis and the inadequate transfer of the pigment from the melanocytes to the nearby keratinocytes

Lenharo, M
