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It also plays a role in protecting B12 from being destroyed by stomach acid, such as in the stomach and intestines.[ref] TCN2 (transcobalamin II, TCN2 gene): TCN2 is a B12 transport protein that moves vitamin B12 from the bloodstream into cells throughout the body

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Magnesium citrate at 200 to 400 mg before bed acts as a gentle osmotic laxative

It binds to insulin which then initiates a cascading pathway of metabolic events through the action of the enzyme phosphatidylinositol-3-kinase and the activation of insulin-1 receptor substrate

doi: 10.1210/jc.2017-01210 52 HjelholtAJCharidemouEGriffinJLPedersenSBGudiksenAPilegaardHet al