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The reversal is documented in the agency's 503A bulk substances reference document, updated May 14, 2026
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The T94 2.61 I/E134 3.49 Q/M257 6.40 Y triple mutant is sensitive to illumination because a small amount of the Schiff base linked material is converted into the 380 nm absorbing species (Fig

The fumarate end product of tyrosine catabolism feeds directly into the TCA cycle for further oxidation