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Further study supported the antiinflammatory potential of bilirubin in the EAE model [64]
The GSH precursor, N-acetylcysteine (NAC), has been used in the treatment of many lung disorders, such as COPD and chronic bronchitis
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Mechanistically, TSA upregulates transcription factor, Krppel-like factor (KLF4) by inhibiting miR-375, activating the STAT6/monocyte chemotactic protein-induced protein pathway to promote M2 polarization, and simultaneously suppressing the NF-B pathway to reduce inflammation
2011 Jun 28;32(2):114-22
