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Annu Rev Pharmacol Toxicol 46:215234 Drevet JR (2006) The antioxidant glutathione peroxidase family and spermatozoa: a complex story

In response to oxidative agents, inflammation, infections or neurodegeneration, astrocytes undergo profound changes in morphology, gene expression and functiona phenomenon known as astrocyte state transition

These natural agents can work in several ways: some are fantastic at calming inflammation, others excel at soothing and coating the delicate gut lining, some provide direct support for mucosal repair, and others help bring the gut microbiome back into harmonious balance

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