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Glossary ATP Adenosine triphosphate AMPK activated Protein Kinase ARDS Acute respiratory distress syndrome AKI Acute kidney injury CARS Compensatory Anti-inflammatory Response Syndrome cGAS Cyclic GMP-AMP synthase cGAMP Cyclic GMP-AMP CPB Cardiopulmonary bypass CRS Cytokine Release Syndrome CKD Chronic Kidney Disease DAMPs Damage-associated molecular patterns MARS Mixed Antagonist Response Syndrome mtDAMPs Mitochondrial damage-associated molecular patterns mtDNA Mitochondrial DNA MyD88 Myeloid differentiation primary response 88 MAS Macrophage Activation Syndrome mPTP mitochondrial permeability transition pore MDSCs Myeloid-derived suppressor cells mTORC mammalian Target of Rapamycin Complex NF-B Nuclear factor kappa-light-chain-enhancer of activated B cells NAD+ Nicotinamide Adenine Dinucleotide NLRP3 NLR family pyrin domain containing 3 NR4A Nuclear receptor subfamily 4 group A ROS Reactive oxygen species RNS Reactive Nitrogen Species STING Stimulator of interferon genes TLR9 Toll-like receptor 9 TOX Thymocyte selection-associated high mobility group box protein IRF3 Interferon regulatory factor 3 TBK1 TANK-binding kinase 1 IL-1 Interleukin-1 beta IL-6 Interleukin-6 IL-1 Interleukin-1 TNF- Tumor necrosis factor-alpha IFN Interferon SIRS Systemic inflammatory response syndrome IR Ischemiareperfusion ICU Intensive care unit the cGAS-STING pathway Cyclic GMP-AMP synthasestimulator of interferon genes pathway PD-1 Programmed cell death protein 1 PD-L1 Programmed cell death ligand 1 POCD Postoperative cognitive dysfunction References 1 BartelsKKarhausenJClambeyETGrenzAEltzschigHK

2009;60(Suppl 7):10714

In some situations, reducing power can be transferred between NADH and NADPH by nicotinamide nucleotide transhydrogenases (NNT) [9, 10]

151 These discoveries not only deepen our understanding of aerobic glycolysis regulatory networks but also, more importantly, reveal the multifaceted roles of metabolic enzymes in the regulation of cellular function

Glutathione is a powerful antioxidant produced naturally in the body