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Uptake of extracellular asparagine prevents the death of glioblastoma cells in response to glutamine depletion by blocking the apoptotic function of a glutamine-induced endoplasmic reticulum stress marker protein, ATF4, and by increasing glutamate-ammonia ligase (GLUL)-mediated glutamine and protein synthesis 116,117

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The investigators reported faster reepithelialization and reduced post-treatment erythema in the GHK-Cu arm compared with standard care, consistent with prior clinical trials of GHK-Cu in diabetic ulcers and Mohs surgical wounds [2]

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However, some of the recommendations have possibly resulted in more harm than good

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