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Melatonin synthesized in the pineal gland is rapidly and pulsatilely released into the bloodstream and cerebrospinal fluid, from where it is distributed to organs and tissues throughout the body. MELATONIN RECEPTORS Activation of melatonin receptors determines the subsequent biological effects

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The neurometabolite levels of Glu, Gln, and GABA were assessed in the anterior cingulate cortex (ACC), thalamus, and right temporo-parietal junction (TPJ), with most quantifications passing quality checks