![localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant](https://www.biorxiv.org/content/biorxiv/early/2022/09/06/2022.09.05.506579/F1.large.jpg)
localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant
Description
Curr Pharm Des 2014;20:1121-1125
![localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs11064-026-04764-0/MediaObjects/11064_2026_4764_Fig11_HTML.png)
Wegovy is administered at a maximum dose of 2.4 mg weekly, whereas Ozempic's maximum dose is 2.0 mg
![localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-018-26296-6/MediaObjects/41598_2018_26296_Fig2_HTML.jpg)
In mammalian cells the NAD + salvage pathway enzymes NAMNT-1 and NAMPT both increase NAD + levels and activate SIRT1-mediated transcription regulation of a number of genes, including TGFB2 (41)
![localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2fc/3849600/c8f84f36b0ee/nihms-531314-f0002.jpg)
This review has primarily focused on research over the past few decades on the metabolic effects of NDDs
![localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant](https://pubs.rsna.org/cms/10.1148/radiol.13130531/asset/images/large/radiol.13130531.fig5b.jpeg)
doi: 10.1186/s10194-021-01381-w 36
![localized nmr spectroscopy glutathione turnover in rat brain Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of [1-13C]Glc at 9.4 T Glutathione as a Potential Neuroprotectant](https://journals.sagepub.com/cms/10.3233/MGC-210062/asset/344bd0e8-492a-4d20-b3be-485d64ebc4b1/assets/graphic/10.3233_mgc-210062-fig1.jpg)
