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Skin flares, joint pain, fatigue, recurrent mouth ulcers, histamine-type reactions, and autoimmune concerns may also require a broader workup

Conversely, patients with effective conventional treatment options available should generally pursue established therapies before considering investigational peptide approaches

While interest in Sermorelin has expanded beyond its original FDA-approved indication, the quality and quantity of evidence supporting many contemporary uses remain variable

Psychiatry 170, 290-298 (2013)

What matters is what is bundled around it: who is supervising your protocol, where the medication came from, whether anyone is following up after the cycle