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HGH reduces insulin sensitivity and can raise blood glucose, potentially leading to insulin resistance with chronic use

Furthermore, the incidence of metabolic disorders affecting tissues such as the liver, heart, and skeletal muscles that solely depend on FAO for metabolism has been reported [33]

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Studies indicate that reconstituted peptides in bacteriostatic water maintain stability and activity profiles comparable to those reconstituted in plain sterile water, with the added benefit of extended multi-use capability

It was previously approved by the FDA for diagnostic evaluation and treatment of pediatric GH deficiency and is now widely used off-label in research and clinical settings to address adult-onset GH insufficiency and age-related hormonal decline