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Description
By designing a thiol-activatable fluorescent gold nanoprobe that can bind to serum protein and be transported to the liver, we non-invasively imaged the biotransformation kinetics in vivo at high specificity and examined this process at the chemical level

A simple method for determination of serum catalase activity and revision of reference range

SIRT6 deacetylates PKM2 to suppress its nuclear localization and oncogenic functions
By periodically suppressing mTOR, rapamycin enhances autophagy (cellular cleanup), improves immune function, and targets the fundamental mechanisms of aging at the cellular level

Too much or too little are both problems for optimal health
