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The three most frequent hyperpigmented disorders include actinic (AL) or solar (SL) lentigines [20,21,22,23,24], PIH [25,26,27], and melasma [28,29,30,31], all sharing an increase in melanin content but each also being characterized by specific features (Fig

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doi: 10.1038/s41598-020-63318-8 29 GanQZSunXYOuyangJM

Bioinformatic and biochemical characterizations of C-S bond formation and cleavage enzymes in the fungus Neurospora crassa ergothioneine biosynthetic pathway