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Dec 2016;266(8):725-736

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

Metal-induced carcinogenesis, oxidative stress and hypoxia signalling

Reid TJ et al

The paradigm of cancer development now emphasizes that carcinogenesis is a result of cumulative genetic and epigenetic changes that collectively endow tumors with traits of adaptability and heterogeneity (Lu et al
