glutathione depletion acetaminophen A new twist to an old tale: novel insights into the differential toxicities of and its regioisomer N-acetyl-meta-aminophenol (AMAP) | Archives of Toxicology Early life acetaminophen exposure, glutathione

Sustained use is what trial protocols approximate

Minich and Brown, 2019

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In contrast, more severe toxicity was observed when rat or human liver slices were incubated with AMAP than when mouse liver slices were incubated with the compound, or when rat and human liver slices were incubated with acetaminophen

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