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Animal studies have shown that high doses of calcium D-glucarate may modulate beta-glucuronidase, and thereby support the process of glucuronidation

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Although its contribution to energy metabolism in the healthy brain is minimal, it is an interesting metabolite which is not only oxidised but also has other direct and collateral effects which make it a molecule of interest for therapeutic purposes

Therefore, viral infections that increase cellular iron content or intestinal iron absorption are likely to cause ferroptosis