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Regarding EE, sonication time and emulsifier concentration showed a synergistic effect, while the solid/lipid ratio had an antagonistic effect

10 mg / 2 mL = 5 mg/mL

It is not extrapolation from a single ingredient study

Mitochondrial base editor induces substantial nuclear off-target mutations

The IgG can interfere with the fetal development and inhibit the complete formation of the BBB of the fetus (Croen et al., 2008)
