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Description
2020, www.sciencedirect.com/science/article/abs/pii/S0976566220304409, Wen Ting Hao, et al
10.1016/j.postharvbio.2020.111270 44 KaharP.IwataT.HirakiJ.ParkE

145 This approach generally alters the gene expression of astrocytesan abundant glial cell type in the area of degenerationto convert them into neurons as a means for localized neuronal replacement

However, most synthetic ATs have not yet progressed to clinical trials

Although current treatments focus on reestablishing perfusion, they offer limited protection against the secondary ROS-mediated injury
