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Moreover, in accordance with what has been discussed above, the lactate secreted by MSCs can not only induce M2 macrophage polarization, but promote the capability of DCs polarizing CD4 + T cells into Th2 cells, implicating the dynamic interaction between M2 macrophages and DCs [104]

Nevertheless, the study was only run for 8 weeks, and higher doses of ashwagandha could have been used

Braun, E., Moosavi, S

Cancer metabolism: The known, unknowns

2.2.3 8-hydroxy-2-deoxyguano-sine (8-OHdG) Reactive oxygen radicals attack the carbon atom at the 8-position of the guanine base in the DNA molecule, producing the oxidation product 8-OHdG
