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IgG antibodies appear later and indicate a past infection or reactivation of the virus

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Kanberg N, Ashton NJ, Andersson LM, Yilmaz A, Lindh M, Nilsson S, Price RW, Blennow K, Zetterberg H, Gissln M (2020) Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19

These documents detail clinical pharmacology, indications, contraindications, warnings, adverse reactions, and drug interactions based on the complete clinical development program

In addition, these changes cause a reduction of cerebral blood flow (CBF) and synaptic dysfunction with the development of neurodegeneration and cognitive impairment (Kamat et al