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Stereochemical consistency is particularly relevant for reference materials intended for structural comparison workflows

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Estimation of TEFs is a critically important part of the risk assessment of environmental mixtures of TCDD, other dioxins, and DLCs, because any environmental sample typically contains a dozen or more similar substances, but often very little TCDD

[3] [35] Direct-acting cholinergic agonists, most notably pilocarpine, stimulate muscarinic acetylcholine receptors directly, whereas indirect-acting cholinergic agents inhibit acetylcholinesterase, thereby prolonging the action of endogenous acetylcholine