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As the first defense against ROS damage, superoxide dismutase (SOD) can effectively eliminate superoxide anion (O 2 ) and reduce oxidative stress by virtue of its unique catalytic site formed by the coordination of metal ions and amino-acid residues 9,10,11

Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, et al

This process underscores the predominant cytoprotective function of GSTs

There is no specific therapy for GCS deficiency, although it would seem prudent to obtain periodic gallbladder ultrasound examinations since affected patients have had cholecystectomies

Guler et al., 2017), signaling pathways and/or metabolic regulation (Hangauer et al., 2017