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[3] The proposed mechanism involves B12 altering the gene expression of skin bacteria ( Cutibacterium acnes ), leading to increased inflammatory compounds

For those who don't care for a shot, oral supplementation with the two active forms of B12, methylcobalamin and adenosylcobalamin, may be as effective as a B12 shot

Interaction with Medications: May interact with certain medications (PPIs, metformin, anticonvulsants)