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The use of parenteral injections can sometimes give rise to toxic reactions as well as allergic type responses with respiratory distress

Diagnosis and Testing Diagnosing vitamin B12 deficiency involves a combination of clinical assessment, medical history, and specific blood tests

The intracellular concentrations of vitamin B12 can be inferred through the total plasma concentration of homocysteine, which can be converted to methionine through an enzymatic reaction that uses 5-methyltetrahydrofolate as the methyl donor group

clinical relevance