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Embodiment 142 The immunoconjugate of embodiment 141, wherein the drug comprises a drug selected from the group consisting of an auristatin, Dolastatin-10, synthetic derivatives of the natural product Dolastatin-10, and maytansine or a maytansine derivative
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In those cells incubated with BSO, CMFDA staining was similar or even higher than in control
The influence of circadian rhythm on metabolic homeostasis, neuroendocrine signaling, immune and oxidative stress responses, tissue repair and autophagy activity is orchestrated by a group of clock genes, with Bmal1 serving as the central regulator
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